Cas:8002-43-5 Molecular Formula:C13H24NO10P Molecular weight:385.304 g/mol Product Application:
Phosphatidylserine (abbreviated Ptd-L-Ser or PS) is a phospholipid component, usually kept on the inner-leaflet, the cytosolic side, of cell membranes by an enzyme called flippase. Annexin-A5 is a naturally-occurring protein with avid binding affinity for PS. Labeled-annexin-A5 enables visualization of cells in the early- to mid-apoptotic state in vitro or in vivo. Another PS binding protein is Mfge8.Technetium-labeled annexin-A5 enables distinction between malignant and benign tumours whose pathology includes a high rate of cell division and apoptosis in malignant compared with a low rate of apoptosis in benign tumors.